Basic Information
ID: ALA4221690
Type: Binding
Description: Inhibition of cathepsin B in human MCF-10A neoT cells assessed as proteolysis of extracellular membrane by measuring decrease in intracellular degradation of DQ-collagen 4 at 50 uM incubated for 2 hrs followed by DQ-collagen addition measured for 2 hrs by propidium iodide staining based flow cytometry relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221690
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.47 | -0.03 | -0.03 |
| 383.45 | -0.11 | -0.11 |
| 407.34 | 2.92 | 2.92 |
| 272.22 | 1.10 | 1.10 |
| 362.35 | 3.01 | 3.01 |
| 298.26 | 1.63 | 1.63 |