Basic Information
ID: ALA4221691
Type: Binding
Description: Inhibition of cathepsin B in human MCF-10A neoT cells assessed as proteolysis of extracellular membrane by measuring decrease in intracellular degradation of DQ-collagen 4 at 12.5 uM incubated for 2 hrs followed by DQ-collagen addition measured for 2 hrs by propidium iodide staining based flow cytometry relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221691
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.52 | 4.10 | 4.10 |
| 447.45 | 3.64 | 3.64 |