Basic Information
ID: ALA4221740
Type: Binding
Description: Inhibition of recombinant human topoisomerase 1 assessed as decrease in relaxation of supercoiled pBR322 DNA at 20 uM after 30 mins by agarose gel electrophoresis relative to camptothecin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221740
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 371.82 | 6.67 | 6.67 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |
| 385.85 | 6.33 | 6.33 |