Basic Information
ID: ALA4221771
Type: Binding
Description: Inhibition of human topoisomerase1-mediated DNA relaxation assessed as DNA intercalation at 5 to 50 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by enzyme addition measured by agarose gel electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221771
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 639.68 | 6.65 | 6.65 |
| 605.58 | 5.18 | 5.18 |
| 573.49 | 3.24 | 3.24 |
| 607.60 | 4.70 | 4.70 |