Basic Information
ID: ALA4221772
Type: Binding
Description: Poison activity at human topoisomerase1 assessed as accumulation of nicked DNA at 5 to 50 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by enzyme addition measured by agarose gel electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221772
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 605.58 | 5.18 | 5.18 |
| 607.60 | 4.70 | 4.70 |