Basic Information
ID: ALA4221773
Type: Binding
Description: Poison activity at human topoisomerase1 assessed as accumulation of nicked DNA at 10 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by enzyme addition measured by agarose gel electrophoresis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221773
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 607.60 | 4.70 | 4.70 |