Basic Information
ID: ALA4221774
Type: Binding
Description: Poison activity at human topoisomerase1 assessed as accumulation of nicked DNA at 20 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by enzyme addition measured by agarose gel electrophoresis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221774
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 573.49 | 3.24 | 3.24 |
| 607.60 | 4.70 | 4.70 |