Assay Report Card

Basic Information

ID: ALA4221776

Type: Binding

Description: Poison activity at human topoisomerase2 assessed as accumulation of linear DNA at 10 to 50 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by substrate addition measured by ethidium bromide staining based agarose gel electrophoresis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
588.561.341.34
386.913.783.78
370.872.812.81