Basic Information
ID: ALA4221852
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM after 60 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: microsome
Target: ADMET(ALA612558)
Document: ALA4219124
Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM after 60 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4221852
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.93 | 7.09 | 7.09 |
| 504.99 | 7.25 | 7.25 |
| 536.89 | 7.22 | 7.22 |
| 504.99 | 6.95 | 6.95 |
| 508.96 | 7.08 | 7.08 |
| 533.91 | 6.49 | 6.49 |
| 518.90 | 7.14 | 7.14 |
| 514.94 | 7.31 | 7.31 |
| 532.93 | 7.39 | 7.39 |
| 525.41 | 7.60 | 7.60 |
| 532.93 | 7.39 | 7.39 |
| 496.95 | 6.52 | 6.52 |
| 532.93 | 7.39 | 7.39 |
| 532.93 | 7.09 | 7.09 |
| 536.89 | 7.22 | 7.22 |
| 536.34 | 6.99 | 6.99 |