Basic Information
ID: ALA4221863
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4221863
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.93 | 7.09 | 7.09 |
| 518.90 | 7.08 | 7.08 |
| 504.99 | 7.25 | 7.25 |
| 536.89 | 7.22 | 7.22 |
| 535.35 | 7.60 | 7.60 |
| 504.99 | 6.95 | 6.95 |
| 508.96 | 7.08 | 7.08 |
| 533.91 | 6.49 | 6.49 |
| 514.94 | 7.25 | 7.25 |
| 518.90 | 7.14 | 7.14 |
| 514.94 | 7.31 | 7.31 |
| 525.41 | 7.60 | 7.60 |
| 532.93 | 7.39 | 7.39 |
| 503.34 | 6.86 | 6.86 |
| 496.95 | 6.52 | 6.52 |
| 532.93 | 7.39 | 7.39 |
| 532.93 | 7.09 | 7.09 |
| 536.89 | 7.22 | 7.22 |
| 536.34 | 6.99 | 6.99 |