Assay Report Card

Basic Information

ID: ALA4221875

Type: ADME

Description: Inhibition of recombinant human COX2 assessed as decrease in PGE2 production at 10 uM using arachidonic acid as substrate preincubated for 15 mins prior to substrate addition for 5 mins relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
536.897.227.22
514.947.317.31
532.937.397.39
532.937.097.09
536.897.227.22
536.346.996.99