Basic Information
ID: ALA4221875
Type: ADME
Description: Inhibition of recombinant human COX2 assessed as decrease in PGE2 production at 10 uM using arachidonic acid as substrate preincubated for 15 mins prior to substrate addition for 5 mins relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome c oxidase subunit 2(ALA6174)
Document: ALA4219124
Inhibition of recombinant human COX2 assessed as decrease in PGE2 production at 10 uM using arachidonic acid as substrate preincubated for 15 mins prior to substrate addition for 5 mins relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4221875
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.89 | 7.22 | 7.22 |
| 514.94 | 7.31 | 7.31 |
| 532.93 | 7.39 | 7.39 |
| 532.93 | 7.09 | 7.09 |
| 536.89 | 7.22 | 7.22 |
| 536.34 | 6.99 | 6.99 |