Basic Information
ID: ALA4221880
Type: Binding
Description: Inhibition of guinea pig mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins followed by substrate addition measured for 1 min
Format: BAO_0000219
Organism: Cavia porcellus
Cell type: CHO
Target: Unchecked(ALA612545)
Document: ALA4219124
Inhibition of guinea pig mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins followed by substrate addition measured for 1 min: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4221880
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.89 | 7.22 | 7.22 |
| 514.94 | 7.31 | 7.31 |
| 532.93 | 7.39 | 7.39 |
| 532.93 | 7.09 | 7.09 |
| 536.89 | 7.22 | 7.22 |
| 536.34 | 6.99 | 6.99 |