Inhibition of rat mPGES1 expressed in CHO cells assessed as reduction in PGE2 production at 10 uM using PGH2 as substrate incubated for 10 mins follow...

Basic Information

ID: ALA4221883

Type: Binding

Description: Inhibition of rat mPGES1 expressed in CHO cells assessed as reduction in PGE2 production at 10 uM using PGH2 as substrate incubated for 10 mins followed by substrate addition measured for 1 min relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: CHO

Target:  Unchecked(ALA612545)

Document:  ALA4219124

Inhibition of rat mPGES1 expressed in CHO cells assessed as reduction in PGE2 production at 10 uM using PGH2 as substrate incubated for 10 mins followed by substrate addition measured for 1 min relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
536.897.227.22
514.947.317.31
532.937.397.39
532.937.097.09
536.897.227.22
536.346.996.99