Basic Information
ID: ALA4222354
Type: Binding
Description: Antagonist activity at human TLR2 expressed in HEK-blue cells assessed as inhibition of Pam3CSK4-induced NF-kappaB activation-mediated SEAP production at 25 uM after 24 hrs by Quanti-blue-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222354
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.28 | 3.81 | 3.81 |
| 263.30 | 4.00 | 4.00 |
| 277.32 | 4.30 | 4.30 |
| 278.31 | 3.93 | 3.93 |
| 250.30 | 3.93 | 3.93 |
| 351.41 | 5.53 | 5.53 |
| 307.40 | 6.26 | 6.26 |
| 265.31 | 4.11 | 4.11 |
| 367.83 | 4.90 | 4.90 |
| 279.26 | 4.46 | 4.46 |
| 227.26 | 3.15 | 3.15 |
| 285.30 | 3.24 | 3.24 |
| 291.31 | 3.99 | 3.99 |
| 331.37 | 4.38 | 4.38 |
| 257.29 | 3.16 | 3.16 |
| 287.36 | 5.11 | 5.11 |
| 303.36 | 4.82 | 4.82 |
| 271.27 | 2.86 | 2.86 |
| 305.33 | 4.30 | 4.30 |
| 325.33 | 6.12 | 6.12 |
| 299.33 | 3.55 | 3.55 |
| 299.33 | 3.55 | 3.55 |
| 365.82 | 5.04 | 5.04 |
| 359.30 | 5.01 | 5.01 |
| 243.26 | 2.86 | 2.86 |
| 345.40 | 4.77 | 4.77 |
| 243.26 | 2.86 | 2.86 |
| 285.30 | 3.16 | 3.16 |
| 379.84 | 5.43 | 5.43 |
| 257.29 | 3.25 | 3.25 |
| 257.25 | 2.55 | 2.55 |
| 271.27 | 2.85 | 2.85 |
| 286.29 | 2.43 | 2.43 |
| 317.39 | 5.21 | 5.21 |
| 307.27 | 4.46 | 4.46 |
| 271.32 | 3.46 | 3.46 |
| 237.30 | 4.11 | 4.11 |
| 271.32 | 3.55 | 3.55 |
| 269.30 | 3.45 | 3.45 |
| 296.37 | 5.59 | 5.59 |
| 385.85 | 6.18 | 6.18 |
| 283.37 | 5.77 | 5.77 |
| 247.30 | 4.30 | 4.30 |
| 243.26 | 2.86 | 2.86 |
| 323.40 | 5.96 | 5.96 |
| 305.33 | 4.30 | 4.30 |
| 261.32 | 4.60 | 4.60 |
| 257.29 | 3.16 | 3.16 |
| 332.28 | 4.64 | 4.64 |
| 303.36 | 4.82 | 4.82 |