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ID: ALA4222355
Type: Binding
Description: Antagonist activity at human TLR2 expressed in HEK-blue cells assessed as inhibition of Pam3CSK4-induced NF-kappaB activation-mediated SEAP production at 50 uM after 24 hrs by Quanti-blue-based assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4222355
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
223.28 | 3.81 | 3.81 |
263.30 | 4.00 | 4.00 |
277.32 | 4.30 | 4.30 |
278.31 | 3.93 | 3.93 |
250.30 | 3.93 | 3.93 |
351.41 | 5.53 | 5.53 |
307.40 | 6.26 | 6.26 |
265.31 | 4.11 | 4.11 |
367.83 | 4.90 | 4.90 |
279.26 | 4.46 | 4.46 |
227.26 | 3.15 | 3.15 |
285.30 | 3.24 | 3.24 |
291.31 | 3.99 | 3.99 |
331.37 | 4.38 | 4.38 |
257.29 | 3.16 | 3.16 |
287.36 | 5.11 | 5.11 |
303.36 | 4.82 | 4.82 |
271.27 | 2.86 | 2.86 |
305.33 | 4.30 | 4.30 |
325.33 | 6.12 | 6.12 |
299.33 | 3.55 | 3.55 |
299.33 | 3.55 | 3.55 |
365.82 | 5.04 | 5.04 |
359.30 | 5.01 | 5.01 |
243.26 | 2.86 | 2.86 |
345.40 | 4.77 | 4.77 |
243.26 | 2.86 | 2.86 |
285.30 | 3.16 | 3.16 |
379.84 | 5.43 | 5.43 |
257.29 | 3.25 | 3.25 |
257.25 | 2.55 | 2.55 |
271.27 | 2.85 | 2.85 |
286.29 | 2.43 | 2.43 |
317.39 | 5.21 | 5.21 |
307.27 | 4.46 | 4.46 |
271.32 | 3.46 | 3.46 |
237.30 | 4.11 | 4.11 |
271.32 | 3.55 | 3.55 |
269.30 | 3.45 | 3.45 |
296.37 | 5.59 | 5.59 |
385.85 | 6.18 | 6.18 |
283.37 | 5.77 | 5.77 |
247.30 | 4.30 | 4.30 |
243.26 | 2.86 | 2.86 |
323.40 | 5.96 | 5.96 |
305.33 | 4.30 | 4.30 |
261.32 | 4.60 | 4.60 |
257.29 | 3.16 | 3.16 |
332.28 | 4.64 | 4.64 |
303.36 | 4.82 | 4.82 |