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Assay Report Card

Basic Information

ID: ALA4222355

Type: Binding

Description: Antagonist activity at human TLR2 expressed in HEK-blue cells assessed as inhibition of Pam3CSK4-induced NF-kappaB activation-mediated SEAP production at 50 uM after 24 hrs by Quanti-blue-based assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
223.283.813.81
263.304.004.00
277.324.304.30
278.313.933.93
250.303.933.93
351.415.535.53
307.406.266.26
265.314.114.11
367.834.904.90
279.264.464.46
227.263.153.15
285.303.243.24
291.313.993.99
331.374.384.38
257.293.163.16
287.365.115.11
303.364.824.82
271.272.862.86
305.334.304.30
325.336.126.12
299.333.553.55
299.333.553.55
365.825.045.04
359.305.015.01
243.262.862.86
345.404.774.77
243.262.862.86
285.303.163.16
379.845.435.43
257.293.253.25
257.252.552.55
271.272.852.85
286.292.432.43
317.395.215.21
307.274.464.46
271.323.463.46
237.304.114.11
271.323.553.55
269.303.453.45
296.375.595.59
385.856.186.18
283.375.775.77
247.304.304.30
243.262.862.86
323.405.965.96
305.334.304.30
261.324.604.60
257.293.163.16
332.284.644.64
303.364.824.82