Basic Information
ID: ALA4222365
Type: Binding
Description: Antagonist activity at human TLR1/2 expressed in HEK-blue cells assessed as inhibition of Pam3CSK4-induced IL-8 mRNA expression at 100 uM preincubated for 1 hr followed by Pam3CSK4 induction measured after 1 hr by qRT-PCR method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222365
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.30 | 3.16 | 3.16 |