Basic Information
ID: ALA4222538
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis IMPDH deltaCBS mutant assessed as reduction in NADH production at 1 mM using IMP as substrate preincubated for 5 mins followed by substrate addition measured for 32 mins in presence of NAD+
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA4222538
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 144.17 | 2.55 | 2.55 |
| 144.18 | 2.08 | 2.08 |
| 142.16 | 2.04 | 2.04 |
| 144.17 | 2.55 | 2.55 |
| 160.17 | 2.25 | 2.25 |
| 184.24 | 2.66 | 2.66 |
| 178.62 | 2.73 | 2.73 |
| 219.26 | 2.82 | 2.82 |
| 159.19 | 1.45 | 1.45 |
| 204.18 | 1.95 | 1.95 |
| 238.09 | 2.42 | 2.42 |
| 165.19 | 1.66 | 1.66 |
| 178.23 | 1.89 | 1.89 |
| 174.20 | 2.55 | 2.55 |
| 164.23 | 2.39 | 2.39 |
| 187.20 | 2.18 | 2.18 |
| 223.07 | 2.84 | 2.84 |
| 238.09 | 2.42 | 2.42 |