Basic Information
ID: ALA4222544
Type: Binding
Description: Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetylated human UBE2M (1 to 12 residues) after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222544
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.41 | 3.47 | 3.47 |
| 353.42 | 3.20 | 3.20 |
| 505.48 | 6.77 | 6.77 |
| 477.53 | 5.73 | 5.73 |
| 431.50 | 5.61 | 5.61 |
| 419.49 | 5.61 | 5.61 |
| 377.41 | 4.49 | 4.49 |
| 377.41 | 4.49 | 4.49 |
| 409.45 | 5.21 | 5.21 |
| 447.55 | 6.39 | 6.39 |
| 433.52 | 6.00 | 6.00 |
| 477.53 | 5.73 | 5.73 |
| 463.50 | 5.34 | 5.34 |
| 447.50 | 5.53 | 5.53 |
| 391.44 | 4.80 | 4.80 |
| 457.50 | 5.13 | 5.13 |
| 473.58 | 6.78 | 6.78 |
| 391.44 | 4.80 | 4.80 |
| 467.54 | 6.40 | 6.40 |
| 461.57 | 6.64 | 6.64 |
| 468.52 | 5.80 | 5.80 |
| 411.86 | 5.14 | 5.14 |
| 411.85 | 5.14 | 5.14 |
| 435.31 | 4.08 | 4.08 |
| 461.57 | 6.78 | 6.78 |
| 447.55 | 6.25 | 6.25 |
| 562.03 | 7.16 | 7.16 |
| 420.48 | 5.01 | 5.01 |
| 483.56 | 4.94 | 4.94 |
| 395.40 | 4.63 | 4.63 |
| 474.55 | 5.86 | 5.86 |
| 447.55 | 6.39 | 6.39 |
| 473.46 | 6.16 | 6.16 |
| 420.48 | 5.01 | 5.01 |
| 497.58 | 5.33 | 5.33 |
| 435.45 | 4.03 | 4.03 |
| 374.49 | 4.26 | 4.26 |
| 525.57 | 6.18 | 6.18 |
| 457.50 | 5.13 | 5.13 |
| 385.47 | 5.07 | 5.07 |
| 387.45 | 4.06 | 4.06 |
| 391.44 | 4.80 | 4.80 |
| 411.86 | 5.14 | 5.14 |
| 371.45 | 4.82 | 4.82 |
| 399.50 | 5.46 | 5.46 |
| 357.88 | 4.43 | 4.43 |
| 425.54 | 5.99 | 5.99 |
| 339.44 | 3.48 | 3.48 |
| 395.40 | 4.63 | 4.63 |
| 431.46 | 4.92 | 4.92 |
| 355.51 | 4.19 | 4.19 |
| 408.55 | 3.30 | 3.30 |
| 391.39 | 4.13 | 4.13 |
| 459.56 | 6.39 | 6.39 |
| 395.40 | 4.63 | 4.63 |
| 385.47 | 5.21 | 5.21 |
| 389.50 | 3.87 | 3.87 |
| 435.46 | 6.13 | 6.13 |
| 447.55 | 6.25 | 6.25 |
| 485.53 | 6.54 | 6.54 |
| 323.44 | 3.78 | 3.78 |
| 511.54 | 6.13 | 6.13 |