Assay Report Card

Basic Information

ID: ALA4222548

Type: Binding

Description: Inhibition of human DCN1-mediated cullin neddylation assessed as reduction in transfer of fluorescein-5-maleimide-tagged NEDD8 from N-terminally acetylated human UBE2M to CUL2-CTD at 12.5 and 50 uM measured for 10 sec by pulse-chase assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
447.556.396.39