Basic Information
ID: ALA4222553
Type: Binding
Description: Inhibition of human DCN1-mediated cullin neddylation assessed as reduction in transfer of fluorescein-5-maleimide-tagged NEDD8 from N-terminally acetylated human UBE2M to CUL2-CTD measured for 10 sec by pulse-chase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222553
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.48 | 6.77 | 6.77 |
| 477.53 | 5.73 | 5.73 |
| 419.49 | 5.61 | 5.61 |
| 377.41 | 4.49 | 4.49 |
| 409.45 | 5.21 | 5.21 |
| 447.55 | 6.39 | 6.39 |
| 433.52 | 6.00 | 6.00 |
| 477.53 | 5.73 | 5.73 |
| 463.50 | 5.34 | 5.34 |
| 420.48 | 5.01 | 5.01 |