Basic Information
ID: ALA4222558
Type: Binding
Description: Inhibition of human NAE1-UBA3 E1 activating enzyme assessed as reduction in CUL3 neddylation by measuring inhibition of UBE2M thiol-ester formation at 50 uM up to 60 mins by pulse-chase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222558
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.55 | 6.39 | 6.39 |
| 433.52 | 6.00 | 6.00 |