Basic Information
ID: ALA4222560
Type: Binding
Description: Inhibition of human RBX1-catalyzed CUL2(CTD) neddylation assessed as reduction in transfer of N-terminal cys-tagged NEDD8 from UBE2M to CUL2-CTD at 12.5 uM measured up to 6 mins by pulse-chase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4222560
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.48 | 6.77 | 6.77 |
| 447.55 | 6.39 | 6.39 |
| 433.52 | 6.00 | 6.00 |
| 477.53 | 5.73 | 5.73 |