Basic Information
ID: ALA4222583
Type: Binding
Description: Antagonist activity at recombinant human P2X3 receptor expressed in Flp-In-293 cells assessed as inhibition of alphabeta-meATP-induced calcium flux preincubated for 10 mins followed by alphabeta-meATP addition measured at 5 sec intervals by Fluo-4 dye based FLIPR assay
Organism: Homo sapiens
Cell type: Flp-In-293
Activity Charts
Bioactivity
Activity Types for Assay ALA4222583
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.46 | 5.28 | 5.28 |
| 420.49 | 3.92 | 3.92 |
| 443.48 | 4.83 | 4.83 |
| 393.46 | 4.31 | 4.31 |
| 429.46 | 4.37 | 4.37 |
| 443.47 | 5.19 | 5.19 |
| 481.53 | 5.34 | 5.34 |
| 417.44 | 4.44 | 4.44 |
| 478.90 | 5.38 | 5.38 |
| 446.46 | 4.52 | 4.52 |
| 402.43 | 3.87 | 3.87 |
| 402.43 | 3.66 | 3.66 |
| 431.47 | 4.69 | 4.69 |
| 459.47 | 4.43 | 4.43 |
| 417.44 | 3.92 | 3.92 |
| 402.43 | 3.87 | 3.87 |
| 458.48 | 5.03 | 5.03 |
| 463.43 | 4.26 | 4.26 |
| 496.46 | 5.40 | 5.40 |
| 417.44 | 4.44 | 4.44 |
| 480.47 | 6.16 | 6.16 |
| 479.89 | 4.77 | 4.77 |