Basic Information
ID: ALA4222800
Type: Functional
Description: In vivo inverse agonist activity at RORgamma in wild type BALB/c ByJ Rj mouse model of imiquimod-induced skin inflammation model assessed as attenuation of imiquimod-induced epidermal hyperplasia at 0.5% administered topically twice daily for 7 days dosed 2 hrs before and 6 hrs after imiquimod administration measured on day 8 by hematoxylin and eosin staining-based histological analysis
Organism: Mus musculus
Strain: BALB/c ByJ Rj
Activity Charts
Bioactivity
Activity Types for Assay ALA4222800
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.71 | 4.94 | 4.94 |