Assay Report Card

Basic Information

ID: ALA4223314

Type: Functional

Description: In vivo inhibition of KDM5 in nude mouse xenografted with human MCF7 cells assessed as increase in H3K4me3 level in tumor at 75 mg/kg, po qd for 5 days measured at 0.5 hrs post last dose by Western blot analysis relative to control

Organism: Mus musculus

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
343.773.513.51