Basic Information
ID: ALA4223319
Type: Binding
Description: Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: G protein-coupled receptor kinase 5(ALA5678)
Document: ALA4219205
Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4223319
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.58 | 3.63 | 3.63 |
| 540.60 | 4.44 | 4.44 |
| 544.63 | 4.91 | 4.91 |
| 547.64 | 3.96 | 3.96 |
| 560.67 | 5.19 | 5.19 |
| 534.51 | 2.43 | 2.43 |
| 530.60 | 4.16 | 4.16 |
| 517.57 | 2.79 | 2.79 |
| 538.58 | 4.36 | 4.36 |
| 519.54 | 1.86 | 1.86 |
| 536.61 | 3.38 | 3.38 |
| 538.54 | 3.09 | 3.09 |
| 548.62 | 3.66 | 3.66 |
| 478.53 | 3.84 | 3.84 |
| 508.55 | 3.09 | 3.09 |
| 520.57 | 3.61 | 3.61 |
| 530.56 | 3.20 | 3.20 |
| 539.57 | 3.78 | 3.78 |
| 538.54 | 3.55 | 3.55 |
| 534.59 | 3.54 | 3.54 |
| 559.65 | 3.50 | 3.50 |
| 542.57 | 4.47 | 4.47 |
| 531.55 | 3.51 | 3.51 |
| 536.56 | 2.12 | 2.12 |
| 531.55 | 3.55 | 3.55 |
| 520.57 | 2.79 | 2.79 |
| 536.61 | 3.38 | 3.38 |
| 546.65 | 4.99 | 4.99 |
| 534.64 | 4.79 | 4.79 |
| 538.58 | 2.10 | 2.10 |
| 520.61 | 5.06 | 5.06 |
| 548.62 | 4.39 | 4.39 |
| 518.51 | 2.84 | 2.84 |
| 548.58 | 3.57 | 3.57 |
| 540.56 | 3.77 | 3.77 |
| 546.56 | 3.13 | 3.13 |
| 545.62 | 3.21 | 3.21 |
| 516.54 | 3.27 | 3.27 |
| 520.61 | 4.91 | 4.91 |
| 540.60 | 4.26 | 4.26 |