Basic Information
ID: ALA4223422
Type: Binding
Description: Binding affinity to CA-SP1 P373S mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring virus yields after 4 to 5 days in presence of 10% FBS by luciferase reporter gene assay
Organism: Human immunodeficiency virus 1
Strain: subtype B NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4223422
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.84 | 8.14 | 8.14 |
| 558.80 | 9.12 | 9.12 |
| 628.94 | 8.71 | 8.71 |
| 614.96 | 9.19 | 9.19 |
| 669.01 | 9.64 | 9.64 |
| 719.09 | 8.75 | 8.75 |
| 759.15 | 9.62 | 9.62 |
| 657.00 | 8.96 | 8.96 |
| 655.02 | 10.11 | 10.11 |
| 727.07 | 9.52 | 9.52 |
| 705.06 | 8.36 | 8.36 |
| 656.01 | 8.53 | 8.53 |
| 628.94 | 8.76 | 8.76 |
| 684.07 | 9.26 | 9.26 |
| 733.12 | 9.09 | 9.09 |
| 671.02 | 9.35 | 9.35 |
| 644.99 | 8.60 | 8.60 |
| 715.03 | 9.29 | 9.29 |
| 614.92 | 8.37 | 8.37 |
| 691.00 | 10.36 | 10.36 |
| 671.07 | 10.74 | 10.74 |
| 601.92 | 9.01 | 9.01 |
| 675.01 | 7.91 | 7.91 |
| 643.01 | 9.97 | 9.97 |
| 637.95 | 9.52 | 9.52 |
| 648.98 | 10.26 | 10.26 |
| 691.06 | 11.15 | 11.15 |
| 628.99 | 9.58 | 9.58 |
| 630.96 | 8.21 | 8.21 |
| 600.93 | 8.97 | 8.97 |
| 669.05 | 10.50 | 10.50 |
| 670.04 | 8.87 | 8.87 |