Basic Information
ID: ALA4223438
Type: Binding
Description: Binding affinity to CA-SP1 P373S/V362I double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring virus yield after 4 to 5 days in presence of 10% FBS by luciferase reporter gene assay
Organism: Human immunodeficiency virus 1
Strain: subtype B NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4223438
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.84 | 8.14 | 8.14 |
| 628.94 | 8.71 | 8.71 |
| 719.09 | 8.75 | 8.75 |