Basic Information
ID: ALA4223546
Type: Binding
Description: Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition measured every 1 min within 8 to 15 mins by FRET assay
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4223546
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 685.90 | 1.47 | 1.47 |
| 467.61 | 6.30 | 6.30 |
| 515.66 | 6.74 | 6.74 |
| 455.51 | 4.19 | 4.19 |
| 441.49 | 4.19 | 4.19 |
| 429.56 | 4.08 | 4.08 |
| 509.69 | 7.47 | 7.47 |
| 439.56 | 5.00 | 5.00 |
| 379.42 | 2.45 | 2.45 |
| 463.58 | 4.57 | 4.57 |
| 433.60 | 5.73 | 5.73 |
| 559.67 | 6.37 | 6.37 |
| 517.59 | 5.93 | 5.93 |
| 511.62 | 5.92 | 5.92 |
| 398.47 | 3.89 | 3.89 |
| 511.62 | 5.02 | 5.02 |
| 398.47 | 3.89 | 3.89 |
| 391.52 | 4.56 | 4.56 |
| 412.49 | 4.07 | 4.07 |
| 441.49 | 4.19 | 4.19 |
| 440.50 | 3.59 | 3.59 |