Assay Report Card

Basic Information

ID: ALA4223815

Type: Functional

Description: In vivo inhibition of SPT in tumors of human HCC1806 cells xenografted in mouse assessed as reduction in 3-KDS levels at 10 mg/kg, po measured after 8 hrs post dose by LC/MS analysis relative to control

Organism: Mus musculus

Cell type: HCC1806

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
533.514.304.30
542.954.464.46