Basic Information
ID: ALA4224051
Type: Binding
Description: Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPH
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4224051
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 265.32 | 1.97 | 1.97 |
| 305.38 | 3.23 | 3.23 |
| 321.38 | 2.32 | 2.32 |
| 279.35 | 2.36 | 2.36 |
| 293.33 | 2.00 | 2.00 |
| 293.37 | 2.75 | 2.75 |
| 277.33 | 2.45 | 2.45 |
| 307.40 | 3.14 | 3.14 |
| 295.35 | 1.86 | 1.86 |
| 317.35 | 2.48 | 2.48 |
| 289.34 | 2.92 | 2.92 |
| 323.40 | 2.12 | 2.12 |
| 291.31 | 2.09 | 2.09 |