Basic Information
ID: ALA4224117
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis GST-tagged PknB expressed in Escherichia coli assessed as reduction in PknB autophosphorylation at 0.24 to 4.8 uM preincubated for 30 mins followed by [gamma32P]ATP addition measured after 30 mins by scintillation counting method
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA4224117
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.56 | 1.87 | 1.87 |
| 448.52 | 2.26 | 2.26 |
| 540.57 | 1.18 | 1.18 |