Basic Information
ID: ALA4224128
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced current response at 0.3 to 300 uM at holding potential -60mV by whole cell voltage clamp method relative to control
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4224128
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.60 | 6.14 | 6.14 |
| 388.55 | 5.36 | 5.36 |
| 444.66 | 6.92 | 6.92 |
| 374.52 | 5.12 | 5.12 |
| 360.49 | 4.73 | 4.73 |
| 402.58 | 5.90 | 5.90 |
| 430.63 | 6.53 | 6.53 |
| 416.60 | 6.29 | 6.29 |
| 402.58 | 5.75 | 5.75 |
| 388.55 | 5.51 | 5.51 |