Assay Report Card

Basic Information

ID: ALA4224129

Type: Binding

Description: Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced current response at 1 to 300 uM at holding potential -60mV by whole cell voltage clamp method relative to control

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
416.565.085.08
402.534.694.69