Basic Information
ID: ALA4224130
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced current response at holding potential -60mV by whole cell voltage clamp method
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4224130
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.56 | 4.93 | 4.93 |
| 444.61 | 5.71 | 5.71 |
| 416.60 | 6.14 | 6.14 |
| 472.67 | 6.64 | 6.64 |
| 388.50 | 4.15 | 4.15 |
| 388.55 | 5.36 | 5.36 |
| 444.66 | 6.92 | 6.92 |
| 458.64 | 6.25 | 6.25 |
| 416.56 | 5.08 | 5.08 |
| 475.65 | ||
| 374.52 | 5.12 | 5.12 |
| 472.67 | 6.49 | 6.49 |
| 360.49 | 4.73 | 4.73 |
| 402.58 | 5.90 | 5.90 |
| 402.53 | 4.69 | 4.69 |
| 458.64 | 6.10 | 6.10 |
| 430.59 | 5.47 | 5.47 |
| 444.61 | 5.86 | 5.86 |
| 402.53 | 4.54 | 4.54 |
| 430.59 | 5.32 | 5.32 |
| 430.63 | 6.53 | 6.53 |
| 416.60 | 6.29 | 6.29 |
| 402.58 | 5.75 | 5.75 |
| 388.55 | 5.51 | 5.51 |