Basic Information
ID: ALA4224131
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced current response at 100 uM at holding potential -60mV by whole cell voltage clamp method relative to control
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4224131
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.56 | 4.93 | 4.93 |
| 444.61 | 5.71 | 5.71 |
| 475.65 | ||
| 458.64 | 6.10 | 6.10 |
| 430.59 | 5.32 | 5.32 |