Basic Information
ID: ALA4229668
Type: Binding
Description: Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 addition and measured after 60 mins by fluorescence polarization assay
Format: BAO_0000357
Organism: Homo sapiens
Target: 14-3-3 protein sigma(ALA1909482)
Document: ALA4229326
Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 addition and measured after 60 mins by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4229668
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 527.85 | 0.79 | 0.79 |
| 400.32 | 0.59 | 0.59 |
| 513.87 | 0.81 | 0.81 |
| 386.34 | 0.61 | 0.61 |
| 506.41 | 1.02 | 1.02 |