Basic Information
ID: ALA4231088
Type: Binding
Description: Inhibition of recombinant N-terminal His6 tagged SUMO-fused Trypanosoma brucei brucei TC221 TAO MTS deletion mutant expressed in Escherichia coli FN102 preincubated for 2 mins followed by ubiquinol-1 addition measured over 2 mins by double beam-dual wavelength UV-spectrophotometry
Organism: Trypanosoma brucei brucei
Strain: TC221
Activity Charts
Bioactivity
Activity Types for Assay ALA4231088
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 153.14 | 0.51 | 0.51 |
| 154.12 | 0.80 | 0.80 |
| 420.93 | 5.22 | 5.22 |
| 168.15 | 1.10 | 1.10 |
| 338.40 | 3.55 | 3.55 |
| 457.45 | 7.11 | 7.11 |
| 719.74 | 9.71 | 9.71 |
| 558.56 | 7.08 | 7.08 |
| 401.34 | 5.55 | 5.55 |
| 691.69 | 8.93 | 8.93 |
| 586.61 | 7.86 | 7.86 |
| 542.56 | 7.41 | 7.41 |
| 556.59 | 7.68 | 7.68 |
| 431.39 | 6.76 | 6.76 |
| 413.40 | 6.66 | 6.66 |
| 422.56 | 5.89 | 5.89 |
| 156.11 | 1.23 | 1.23 |
| 429.40 | 6.33 | 6.33 |
| 378.51 | 5.44 | 5.44 |
| 474.55 | 5.42 | 5.42 |
| 446.50 | 4.64 | 4.64 |
| 289.12 | 2.43 | 2.43 |
| 470.61 | 6.86 | 6.86 |
| 542.56 | 7.37 | 7.37 |
| 530.66 | 6.98 | 6.98 |
| 502.60 | 6.20 | 6.20 |
| 705.71 | 9.24 | 9.24 |
| 675.69 | 9.26 | 9.26 |
| 392.54 | 5.71 | 5.71 |
| 427.42 | 6.93 | 6.93 |
| 498.66 | 7.41 | 7.41 |
| 693.68 | 9.36 | 9.36 |
| 443.42 | 6.64 | 6.64 |
| 152.15 | 1.40 | 1.40 |
| 689.72 | 9.53 | 9.53 |
| 317.18 | 3.21 | 3.21 |