Basic Information
ID: ALA4231140
Type: Binding
Description: Inhibition of recombinant human His-tagged KDR cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression system using Z'-LYTE-Tyr1 as substrate measured after 1 hr by Z'-LYTE assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Vascular endothelial growth factor receptor 2(ALA279)
Document: ALA4229346
Inhibition of recombinant human His-tagged KDR cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression system using Z'-LYTE-Tyr1 as substrate measured after 1 hr by Z'-LYTE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4231140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.46 | 4.52 | 4.52 |
| 389.40 | 5.52 | 5.52 |
| 381.46 | 4.52 | 4.52 |
| 415.90 | 5.17 | 5.17 |
| 404.72 | 5.91 | 5.91 |
| 355.85 | 5.15 | 5.15 |
| 309.37 | 4.63 | 4.63 |
| 321.41 | 4.50 | 4.50 |
| 351.43 | 4.51 | 4.51 |
| 343.81 | 5.29 | 5.29 |
| 393.82 | 6.17 | 6.17 |
| 339.40 | 4.64 | 4.64 |
| 351.43 | 4.51 | 4.51 |
| 370.27 | 5.26 | 5.26 |
| 360.27 | 5.80 | 5.80 |
| 355.85 | 5.15 | 5.15 |
| 411.48 | 4.53 | 4.53 |
| 400.30 | 5.26 | 5.26 |
| 385.88 | 5.16 | 5.16 |
| 359.38 | 5.51 | 5.51 |
| 325.82 | 5.15 | 5.15 |