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Assay Report Card

Basic Information

ID: ALA4231164

Type: Binding

Description: Reversible inhibition of recombinant human E1 expressed in Escherichia coli BL21(DE3) assessed as reduction in biotin-labelled ubiquitin-E1 conjugate formation at 100 uM pretreated for 60 mins followed by 2.5 uM biotin-labelled ubiquitin addition for 30 mins and subsequent 5 uM biotin-labelled ubiquitin addition by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
496.654.484.48