Basic Information
ID: ALA4231438
Type: Functional
Description: Gametocytocidal activity against Plasmodium falciparum 3D7 elo1-pfs16-CBG99 late-stage (4 to 5) gametocytes assessed as inhibition of parasite viability after 72 hrs by luciferase reporter assay
Organism: Plasmodium falciparum
Strain: 3D7 elo1-pfs16-CBG99
Activity Charts
Bioactivity
Activity Types for Assay ALA4231438
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 554.73 | 1.16 | 1.16 |
| 319.86 | 2.50 | 2.50 |
| 383.72 | 4.45 | 4.45 |
| 295.39 | 2.91 | 2.91 |
| 349.40 | 3.86 | 3.86 |
| 383.72 | 4.45 | 4.45 |
| 385.69 | 3.24 | 3.24 |
| 371.71 | 4.40 | 4.40 |
| 300.40 | 3.04 | 3.04 |
| 288.37 | 3.17 | 3.17 |
| 338.37 | 4.05 | 4.05 |
| 380.92 | 5.36 | 5.36 |
| 498.29 | 6.12 | 6.12 |
| 270.38 | 3.04 | 3.04 |
| 399.79 | 4.92 | 4.92 |
| 399.79 | 4.92 | 4.92 |
| 286.38 | 2.74 | 2.74 |
| 349.27 | 3.80 | 3.80 |
| 380.92 | 5.36 | 5.36 |
| 422.19 | 4.55 | 4.55 |
| 304.82 | 3.69 | 3.69 |
| 305.81 | 2.21 | 2.21 |
| 339.30 | 3.75 | 3.75 |