Basic Information
ID: ALA4231528
Type: Functional
Description: Antagonist activity at human beta1 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induced intercellular calcium mobilization pre-incubated for 10 mins before isoproterenol addition by Fluo-4AM dye-based fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4231528
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.52 | 3.99 | 3.99 |
| 476.58 | 3.54 | 3.54 |
| 497.62 | 2.70 | 2.70 |
| 512.63 | 2.66 | 2.66 |
| 443.55 | 3.92 | 3.92 |
| 475.59 | 3.08 | 3.08 |
| 465.58 | 3.54 | 3.54 |
| 432.56 | 4.00 | 4.00 |
| 461.56 | 3.15 | 3.15 |
| 454.59 | 3.62 | 3.62 |
| 449.62 | 4.63 | 4.63 |
| 444.54 | 4.38 | 4.38 |
| 418.54 | 4.07 | 4.07 |