Basic Information
ID: ALA4231613
Type: Binding
Description: Inhibition of FLAP in A23187-stimulated human neutrophils assessed as remaining enzyme activity by measuring 5-LO product formation at 1 uM preincubated for 15 mins followed by A23187 and arachidonic acid addition and measured after 10 mins by UV based RP-HPLC analysis (Rvb = 100%)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4231613
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.93 | 6.48 | 6.48 |
| 505.06 | 7.33 | 7.33 |
| 446.98 | 6.79 | 6.79 |
| 464.96 | 5.43 | 5.43 |
| 478.99 | 6.00 | 6.00 |
| 401.90 | 6.06 | 6.06 |
| 427.98 | 7.27 | 7.27 |
| 523.08 | 8.45 | 8.45 |
| 442.01 | 7.35 | 7.35 |
| 445.99 | 6.19 | 6.19 |
| 487.00 | 6.43 | 6.43 |
| 464.96 | 5.43 | 5.43 |
| 411.90 | 5.70 | 5.70 |
| 425.92 | 5.75 | 5.75 |
| 462.06 | 6.72 | 6.72 |
| 477.00 | 6.55 | 6.55 |
| 461.01 | 6.72 | 6.72 |
| 523.08 | 8.45 | 8.45 |
| 475.03 | 7.11 | 7.11 |
| 487.00 | 6.43 | 6.43 |
| 485.03 | 7.45 | 7.45 |
| 471.00 | 7.14 | 7.14 |
| 482.05 | 5.74 | 5.74 |
| 464.96 | 5.43 | 5.43 |
| 411.90 | 5.70 | 5.70 |
| 461.01 | 6.72 | 6.72 |
| 463.97 | 6.04 | 6.04 |
| 471.01 | 6.27 | 6.27 |
| 446.98 | 6.79 | 6.79 |
| 523.08 | 8.45 | 8.45 |
| 442.01 | 7.35 | 7.35 |
| 475.03 | 7.11 | 7.11 |
| 530.09 | 7.91 | 7.91 |
| 503.07 | 7.80 | 7.80 |