Assay Report Card

Basic Information

ID: ALA4231614

Type: Binding

Description: Inhibition of FLAP in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187 and arachidonic acid addition and measured after 10 mins by UV based RP-HPLC analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
402.977.097.09
399.936.486.48
505.067.337.33
446.986.796.79
464.965.435.43
478.996.006.00
401.906.066.06
427.987.277.27
523.088.458.45
442.017.357.35
445.996.196.19
487.006.436.43
464.965.435.43
411.905.705.70
425.925.755.75
462.066.726.72
477.006.556.55
461.016.726.72
523.088.458.45
475.037.117.11
487.006.436.43
485.037.457.45
471.007.147.14
482.055.745.74
464.965.435.43
411.905.705.70
461.016.726.72
463.976.046.04
471.016.276.27
446.986.796.79
523.088.458.45
476.975.905.90
442.017.357.35
475.037.117.11
530.097.917.91
503.077.807.80