Basic Information
ID: ALA4231622
Type: Binding
Description: Inhibition of FLAP in A23187-stimulated human neutrophils assessed as remaining enzyme activity by measuring 5-LO product formation at 10 uM preincubated for 15 mins followed by A23187 and arachidonic acid addition and measured after 10 mins by UV based RP-HPLC analysis (Rvb = 100%)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4231622
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.90 | 5.70 | 5.70 |
| 425.92 | 5.75 | 5.75 |
| 411.90 | 5.70 | 5.70 |
| 442.01 | 7.35 | 7.35 |