Basic Information
ID: ALA4231713
Type: Binding
Description: Inhibition of GST-tagged human c-MET preincubated for 20 mins followed by [33P]-ATP addition and measured after 2 hrs by Hot-Spot kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4231713
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 428.48 | 4.47 | 4.47 |
| 361.43 | 3.93 | 3.93 |
| 378.42 | 3.32 | 3.32 |
| 378.42 | 3.32 | 3.32 |
| 490.55 | 5.63 | 5.63 |
| 443.41 | 4.41 | 4.41 |
| 420.46 | 2.13 | 2.13 |
| 392.44 | 3.33 | 3.33 |
| 390.43 | 3.38 | 3.38 |
| 446.47 | 4.61 | 4.61 |
| 383.44 | 1.30 | 1.30 |
| 442.50 | 4.48 | 4.48 |
| 397.46 | 1.64 | 1.64 |
| 446.54 | 4.91 | 4.91 |
| 436.50 | 3.44 | 3.44 |
| 458.50 | 4.48 | 4.48 |
| 419.47 | 4.00 | 4.00 |
| 393.43 | 2.72 | 2.72 |
| 425.52 | 1.89 | 1.89 |
| 407.43 | 4.13 | 4.13 |
| 407.43 | 4.13 | 4.13 |
| 432.51 | 4.20 | 4.20 |
| 419.47 | 4.00 | 4.00 |