Basic Information
ID: ALA4232614
Type: Binding
Description: Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4232614
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.79 | 3.09 | 3.09 |
| 279.34 | 3.53 | 3.53 |
| 219.29 | 1.47 | 1.47 |
| 283.35 | 0.80 | 0.80 |
| 281.36 | 3.04 | 3.04 |
| 348.23 | 4.84 | 4.84 |
| 311.39 | 3.05 | 3.05 |
| 358.24 | 4.29 | 4.29 |
| 348.45 | 4.14 | 4.14 |
| 377.45 | 2.88 | 2.88 |
| 362.43 | 3.72 | 3.72 |
| 258.32 | 1.63 | 1.63 |
| 334.42 | 3.20 | 3.20 |
| 380.45 | 3.54 | 3.54 |
| 282.35 | 2.44 | 2.44 |
| 334.42 | 3.83 | 3.83 |
| 320.40 | 3.52 | 3.52 |
| 389.29 | 4.83 | 4.83 |
| 354.84 | 4.18 | 4.18 |
| 319.41 | 3.06 | 3.06 |
| 389.29 | 4.83 | 4.83 |
| 380.45 | 3.54 | 3.54 |
| 247.30 | 1.38 | 1.38 |
| 354.84 | 4.18 | 4.18 |
| 321.38 | 2.92 | 2.92 |
| 412.49 | 5.31 | 5.31 |
| 347.34 | 4.55 | 4.55 |
| 335.41 | 3.63 | 3.63 |
| 311.39 | 3.05 | 3.05 |
| 321.38 | 2.92 | 2.92 |
| 313.79 | 4.19 | 4.19 |
| 355.44 | 5.20 | 5.20 |
| 334.42 | 3.83 | 3.83 |
| 345.41 | 3.39 | 3.39 |
| 350.34 | 3.45 | 3.45 |
| 380.45 | 3.54 | 3.54 |
| 334.42 | 3.83 | 3.83 |
| 348.45 | 4.14 | 4.14 |
| 334.42 | 3.83 | 3.83 |
| 410.52 | 5.11 | 5.11 |
| 371.44 | 4.07 | 4.07 |
| 388.39 | 4.54 | 4.54 |
| 350.42 | 3.53 | 3.53 |
| 300.41 | 2.66 | 2.66 |
| 380.45 | 3.54 | 3.54 |
| 377.45 | 2.88 | 2.88 |
| 377.47 | 4.13 | 4.13 |
| 322.37 | 2.31 | 2.31 |
| 307.35 | 3.53 | 3.53 |
| 389.29 | 4.83 | 4.83 |
| 364.45 | 3.84 | 3.84 |
| 350.34 | 3.45 | 3.45 |
| 389.29 | 4.83 | 4.83 |
| 233.32 | 1.86 | 1.86 |
| 347.34 | 4.55 | 4.55 |
| 332.41 | 3.59 | 3.59 |
| 404.39 | 4.42 | 4.42 |
| 345.41 | 3.39 | 3.39 |
| 348.45 | 4.14 | 4.14 |
| 247.34 | 2.24 | 2.24 |
| 286.38 | 2.41 | 2.41 |
| 380.45 | 3.54 | 3.54 |
| 363.34 | 4.43 | 4.43 |
| 388.39 | 4.54 | 4.54 |
| 388.39 | 4.54 | 4.54 |
| 350.42 | 3.53 | 3.53 |
| 371.44 | 4.07 | 4.07 |
| 350.42 | 3.53 | 3.53 |
| 322.37 | 2.31 | 2.31 |
| 358.24 | 4.29 | 4.29 |
| 424.50 | 4.75 | 4.75 |
| 302.40 | 2.49 | 2.49 |
| 399.29 | 4.28 | 4.28 |
| 332.41 | 3.59 | 3.59 |
| 348.45 | 4.14 | 4.14 |
| 321.38 | 2.92 | 2.92 |
| 354.84 | 4.18 | 4.18 |
| 354.84 | 4.18 | 4.18 |
| 305.38 | 3.13 | 3.13 |
| 333.43 | 3.45 | 3.45 |
| 348.23 | 4.84 | 4.84 |
| 345.41 | 3.39 | 3.39 |
| 348.45 | 4.14 | 4.14 |
| 334.42 | 3.83 | 3.83 |
| 321.38 | 2.92 | 2.92 |
| 354.84 | 4.18 | 4.18 |
| 311.39 | 3.05 | 3.05 |
| 389.29 | 4.83 | 4.83 |
| 334.42 | 3.83 | 3.83 |
| 322.37 | 2.31 | 2.31 |
| 368.87 | 3.85 | 3.85 |
| 377.47 | 4.13 | 4.13 |
| 348.45 | 4.14 | 4.14 |