Basic Information
ID: ALA4233137
Type: Binding
Description: Inhibition of N-[3',6'-dihydroxy-3-oxo-3H-spiro(2-benzofuran-1,9'-xanthen)-5-yl]-N'-[2-(4-{4-[N-(2-chloro-6-methylphenyl)-5-carboxamido]-thiazol-2-yl})-amino-2-methyl-pyrimid-6-yl)piperazinyl]-ethyl]thiourea binding to human PKMYT1 kinase doamin expressed in Escherichia coli BL21 after 120 mins by fluorescence polarization asay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4233137
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.76 | 4.04 | 4.04 |
| 530.46 | 5.19 | 5.19 |
| 512.44 | 5.77 | 5.77 |
| 482.37 | 4.88 | 4.88 |
| 542.04 | 3.94 | 3.94 |
| 488.02 | 3.31 | 3.31 |
| 268.32 | 2.67 | 2.67 |
| 289.34 | 3.10 | 3.10 |
| 328.39 | 3.40 | 3.40 |
| 345.37 | 2.94 | 2.94 |
| 425.51 | 3.18 | 3.18 |
| 438.92 | 3.81 | 3.81 |
| 520.50 | 5.52 | 5.52 |
| 313.36 | 4.75 | 4.75 |
| 429.28 | 5.49 | 5.49 |
| 500.61 | 2.89 | 2.89 |
| 458.53 | 2.69 | 2.69 |
| 327.39 | 5.05 | 5.05 |