Basic Information
ID: ALA4233176
Type: Binding
Description: Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholesterol
Organism: Mus musculus
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA4233176
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.78 | 9.79 | 9.79 |
| 393.57 | 6.21 | 6.21 |
| 501.73 | 7.29 | 7.29 |
| 468.62 | 7.06 | 7.06 |
| 425.60 | 6.76 | 6.76 |
| 398.60 | 6.66 | 6.66 |
| 423.63 | 7.10 | 7.10 |
| 440.61 | 7.07 | 7.07 |
| 440.68 | 7.83 | 7.83 |
| 467.68 | 7.43 | 7.43 |
| 481.71 | 7.43 | 7.43 |
| 482.65 | 7.15 | 7.15 |
| 424.61 | 7.37 | 7.37 |
| 367.52 | 5.54 | 5.54 |
| 410.58 | 6.98 | 6.98 |
| 440.61 | 7.07 | 7.07 |
| 482.76 | 9.00 | 9.00 |
| 454.64 | 6.86 | 6.86 |
| 549.87 | 10.61 | 10.61 |
| 451.68 | 7.88 | 7.88 |
| 412.62 | 7.05 | 7.05 |
| 409.60 | 6.71 | 6.71 |
| 467.68 | 7.43 | 7.43 |
| 481.71 | 7.43 | 7.43 |
| 482.65 | 7.15 | 7.15 |
| 467.68 | 7.43 | 7.43 |
| 452.66 | 8.15 | 8.15 |
| 468.62 | 7.06 | 7.06 |
| 382.53 | 6.20 | 6.20 |
| 454.71 | 8.22 | 8.22 |
| 440.61 | 7.07 | 7.07 |
| 479.73 | 8.66 | 8.66 |
| 468.62 | 7.06 | 7.06 |
| 481.71 | 7.43 | 7.43 |
| 496.79 | 9.39 | 9.39 |
| 440.61 | 7.07 | 7.07 |
| 454.64 | 6.86 | 6.86 |
| 550.85 | 10.88 | 10.88 |
| 482.65 | 7.15 | 7.15 |
| 566.92 | 11.35 | 11.35 |
| 384.57 | 6.27 | 6.27 |
| 437.65 | 7.49 | 7.49 |
| 425.60 | 6.76 | 6.76 |
| 368.50 | 5.81 | 5.81 |
| 466.69 | 8.54 | 8.54 |
| 438.64 | 7.76 | 7.76 |
| 426.65 | 7.44 | 7.44 |
| 468.73 | 8.61 | 8.61 |
| 465.71 | 8.27 | 8.27 |
| 425.60 | 6.76 | 6.76 |
| 492.61 | 8.38 | 8.38 |
| 467.68 | 7.43 | 7.43 |
| 454.64 | 6.86 | 6.86 |
| 454.64 | 6.86 | 6.86 |
| 395.57 | 6.32 | 6.32 |
| 432.59 | 5.54 | 5.54 |
| 468.62 | 7.06 | 7.06 |
| 438.64 | 7.67 | 7.67 |
| 396.56 | 6.59 | 6.59 |
| 480.72 | 8.93 | 8.93 |
| 481.71 | 7.43 | 7.43 |
| 482.65 | 7.15 | 7.15 |
| 425.60 | 6.76 | 6.76 |