Basic Information
ID: ALA4233619
Type: Binding
Description: Poison activity at recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex by measuring concentration required to generate 10% double-stranded DNA breaks using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4233619
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.56 | 1.34 | 1.34 |
| 655.79 | 1.78 | 1.78 |
| 613.71 | 0.74 | 0.74 |
| 641.77 | 1.52 | 1.52 |
| 627.74 | 1.13 | 1.13 |
| 584.67 | 1.54 | 1.54 |
| 643.73 | 2.37 | 2.37 |